Brown-Séquard syndrome – causes, symptoms, diagnosis, treatment, pathology


What is Brown-Séquard syndrome? Brown-Séquard syndrome is a condition associated with hemisection or damage to one half of the spinal cord, resulting in a loss of sensations like pain, temperature, touch, as well as paralysis or loss of muscle function in some parts of the body.
Find more videos at

Study better with Osmosis Prime. Retain more of what you’re learning, gain a deeper understanding of key concepts, and feel more prepared for your courses and exams. Sign up for a free trial at

Subscribe to our Youtube channel at

Get early access to our upcoming video releases, practice questions, giveaways and more when you follow us on social:

Thank you to our Patreon supporters:
Sumant Nanduri
Omar Berrios
Alex Wright
Suzanne Peek
Arfan Azam
Mingli Féng

Osmosis Vision: Empowering the world’s caregivers with the best learning experience possible.


Xem thêm bài viết khác:


  1. Thank you so much I was having some difficulties with the understanding of that syndrome Thank you so much i don't even know how to thank you more than like this if i could i will do it 🙏🏼❤️

  2. Sorry but I think when you mean Lower Motor Neuron at minute 6:00 you should mean Upper Motor Neuron instead, because they come from higher segments in the Spinal Cord, therefore that’s an Upper motor neuron Lesion opposed to the fact of the Lower Motor Neuron Lesion that only happens at the segment level like you explained well short after, that will cause Flaccid Paralysis.

  3. Thankyou so much for keeping me focused in the middle of night , you helped me so much by not spending hours to understand .

  4. Just came through this vid. Good briefing. Here’s the answer to the most common doubt i noticed in comments regarding the symptomology of hemisectioning of corticospinal tract.
    Before we start, heres a basic concept u need to keep in mind.
    What does a motor neurone do?
    When triggered It ALWAYS contracts a muscle.
    To relax a muscle, the motor neurone needs to be inactive.
    Now Grab a paper and a pencil:

    Draw a brain and a spinal cord. Now graduate the spinal cord to thoracic vertebral columns, T1, T2, T3…….T12.
    Next, draw a corticospinal tract (just two to three vertical lines from the brain running down through the spinal cord). These are UMN. Draw a tiny synapses at T11 and draw another neurone from T11 extending laterally. These are LMN.
    Now, scribble two horizontal lines. The first at T5 and the second at T11. These horizontal lines depict sites of injuries.
    Now look at T5. What’s injured there?
    The UMN are injured. The LMN are fine and functioning. What do motor neurones do? They ALWAYS contract a muscle. These fine and functioning LMN are now stuck in an indefinite triggered phase. Sooo, they contract the muscles. That’s spastic paralysis. And this is referred to as UMN weakness.

    Now to T11. What’s injured?
    The LMN are injured. The UMN are fine but are incapable of transmitting signals to the skeletal muscles due to damage to LMN.
    What do motor neurones do?
    They ALWAYS contract.
    But the LMN are damaged. They can’t contract a muscle now. The muscle goes flaccid. That’s flaccid paralysis also referred to as LMN weakness.

    And heres a clinical picture to it on how to determine site of injury if the injury isn’t too evident.

    Let’s say you notice a discrepancy in midback, abdominal muscles and below.
    The midback and abdominal muscles are innervated by T5 segment of spinal column.
    Now use common sense. The corticospinal tract is a whole grouped bunch of fibres extending down in unison from the brain, through the spinal cord and THEN exiting the spinal cord to extend and innervate their destined muscles.
    For all neurones innervating muscle groups below T5, what group of neurone is injured?
    The UMN! So all these muscles suffer spastic paralysis.
    But at the level of T5, for those specific group of muscles innervated by T5, the LMN are injured, and so therefore, only that group of muscles suffer flaccid paralysis.
    You are welcome.

  5. Awesome video!
    But note that the central axons of the first order neurons in the spinothalamic tract give off ascending and descending branches BEFORE they enter the dorsal horn (via the tract of Lissauer) and THEN they synapse on the 2nd order neuron.

  6. Thank you so much for this video! I've been trying to understand this syndrome and I couldn't do it so well, but now I'm good! God bless you all! ❤️🧠📖

  7. Thank you. I have B.S.S. 5yrs. now and this video I just saw told me so much more than my doctor! Now what to do about it.

  8. Really good & informative video but not all the pathway details are imp.
    As a student interested in neurology i loved those details but other students might have difficulty with it

    And as always thank you 🌸

  9. As a brazilian medical student, I want to say thank you for this incredible video. Such a clean, smooth and organized video.

  10. at 6.10 , its upper motor neuron lesion causing spasticity.and at the level of lesion it has flaccid paralysis bcoz of lower motor neuron lesion

  11. Hi, am physiotherapists from Nigeria, I really find your video interesting. Keep the good job.
    But I will suggest if you can expand your scope of video to the field of physical therapy.
    Pls I just wanna you to start doing videos in physical therapy. Thanks

  12. Such a great video, guys! Thank you!
    There is one mistake I've noticed : 3:32 fibres of Spino-thalamic tract after they cross to controlateral side, in fact, they continue in a FRONT-LATERAL bandle of white matter in spinal cord (not at the back as it can appear from the video)
    That's important to mention
    All the rest is better than any tutorial I've seen
    Keep on doing medical studies more fun!

  13. A correction required !
    Thank you for the video.
    In 3:20, you've described first order neutrons for pain & temperature relaying in dorsal horn. Should it not be on the Lateral horn ?

  14. Great video but I do have one question. Why if there was a lesion or injury to the right side of the spinal cord cause paralysis on the ipsilateral side. Wouldn't it be the contralateral side be affected because the right side of the brain controls the left side of the body? I know all the exam questions I've taken says ipsilateral motor loss and contralateral temperature/pain loss, but theoretically, it should be the opposite. Can anyone explain this to me?

  15. Hello, is it possible to have Brown Sequard Syndrome with no flexion of the leg (0/5) but with extension (2/5)? Thank you!

  16. I was diagnosed with multiple sclerosis 1 month after I turned 45. My grandma is 96 and had it since she was in her 20s. I have been on Copaxone, the first year was daily and now I am on 40 mg, 3 times a week. It made a tremendous difference for me. Although the fatigue is what really gets to me. When I do too much, I do start to feel weak. My MS got significantly worse and unbearable Last year, a family friend told me about Organic Herbal clinic and their successful MS TREATMENT, I visited their website ww w . organicherbalclinic. co m and ordered their MS Formula, i am happy to report the treatment effectively treated and reversed my Multiple Sclerosis(MS)), most of the symptoms stopped, I'm able to walk and eat well, sleep well and exercise regularly., I'm pretty active now and my attitude is extremely positive.

  17. FYI any spinal cord injuries or diseases are completely covered under VA help, if you are a honorably discharged military service member

  18. great video!! Thanks a lot, but I guess, you`ve got a little mistake there, [3:32] if this is the spinothalamic tract, the 2nd order axon should cross the spinal cord and join spinothalamic tract in the anterior portion of the spinal cord – you visualize that it goes in the posterior part of spinal cord 🙂 hope I'm right 🙂


Please enter your comment!
Please enter your name here